On Wednesday night, the Sixers will be in Cleveland to take on the Cavaliers. The Sixers are coming off a home loss to the Denver Nuggets where the Sixers won the first quarter by 15 points. They took a seven-point lead into the fourth quarter and lost by four. It was pretty desolate. The loss dropped the Sixers to 41-26. They are 3.5 games out of first place in the conference and one game ahead of fifth place, i.e., they are one game from being on the road in the first Rond of the playoffs. It’s not great.

As for the Cavaliers, their early-season success is in a slow ebb. They are 39-29 and in sixth place in the Eastern Conference.

Let’s get into our Sixers vs. Cavaliers betting pick with player prop predictions, odds, and analysis for this March 16, 2022 matchup.

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Sixers vs. Cavaliers Betting Pick (March 16, 2022)

As the old adage goes, there are lies, damned lies, and statistics. The Sixers are 15 games over .500 and have won seven of their last ten. That’s good, right? Sure, if you don’t look at the three losses, which have come in the past five games.

The Sixers were thoroughly outplayed in Miami on March 5. They were embarrassed on national television by Brooklyn at home a week ago. Monday night’s loss to the Nuggets, again at home, was less an embarrassment than a warning. The Sixers still can’t hold a lead, they still don’t have closers, and they still have defensive lapses at all the wrong times.

The schedule-makers concurrently helped the Sixers and screwed the Sixers with tonight’s game. It had to be aggravating to leave Philadelphia just to go to Cleveland for one mid-week game when the next three games will be home games. Then again, they get Cleveland when they are missing center Jarrett Allen, a big who might have slowed Joel Embiid down tonight.

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Sixers vs. Cavaliers Odds

Here’s the line for the Sixers and Cavaliers at FanDuel Sportsbook:

  • Point Spread: Sixers -2 (-110), Cavaliers +2 (-110)
  • Moneyline: Sixers -130, Cavaliers +110
  • Total: 219.5

Bets We Like With a Sixers Win

Sixers to Win and Over 219.5 Total Points (+217, FanDuel Sportsbook)

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If you’re convinced that the Sixers will win the game (which we are not), tack in onto the over. The last four Sixers games have gone over, even though the game against the Nuggets only beat the number by half a point. That’s all it takes. This prop is on the low side because the Cavaliers have the second-best defense in the league based on opponents’ points per game (103.8). The Sixers cannot expect to win a grind-it-out game based on recent evidence. They’re going to need to hit shots in bunches to win this game.

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Bets We Like Independent of Outcome

James Harden Double Double (-125, Caesars Sportsbook)

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Harden’s points over/under is 22.5, which is a little more than we wanted to take on. So instead, we’ll take a shot with the double double. Harden has posted a double double in four of the seven games he has played with the Sixers, and in one of the games where he missed it, he posted a 26/9/9. This bet seems safer than his points line, so we’re taking it.

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Darius Garland Over 2.5 Three-Point Field Goals (+120, DraftKings Sportsbook)

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Garland has made three or more three-pointers in nine of his last 12 games. He is also putting up a lot of triples — a whopping 84 attempts over that 12-game span, an even seven per game. Garland probably saw the footage from Monday night, where the Sixers gave up 13 threes to the Nuggets, who shot them at almost 40% in that game. We would like this prop at even money, so getting it at +120 is very attractive.

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Lauri Markkanen Over 14.5 Points (-125, FOX Bet)

Here’s another sort of curious line from the books tonight. Markkanen has scored 15 or more in each of his last four contests, and in seven of his last 11. The Sixers are a decent defensive team, but they don’t really have a stopper for a seven-footer who doesn’t live exclusively in the low block.

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Sixers vs. Cavaliers Prediction

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Sometimes it’s just this simple: We trust the Sixers to scratch out a win here, for the most part, but we really don’t trust them enough to lay points to a playoff team on the road. As we have noted before, you should really only take points if you think the underdog has a chance to win the game. The Cavaliers could absolutely win this game outright, so the points are just insurance.

Pick: Cavaliers +3 (-113, Barstool Sportsbook)

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