
Sixers vs. Lakers Betting Odds, Picks, Prediction (March 23, 2022)
On Wednesday night, the Sixers are in Tinseltown to play the Los Angeles Lakers. The Sixers posted an inexplicable win over the Eastern Conference-leading Miami Heat on Monday night despite missing both Joel Embiid and James Harden. The win pulled the Sixers to within 2.5 games of the conference lead, though they still trail the Milwaukee Bucks by half a game. The Lakers are mathematically locked out of the first six playoff spots in the Western Conference. They are hanging on grimly to the ninth seed and the playoff play-in.
Let’s get into our Sixers vs. Lakers betting pick with player prop predictions, odds, and analysis for this March 23, 2022 matchup.

Sixers vs. Lakers Betting Pick (March 23, 2022)
In the modern era, the only great Sixers are players who had no choice but to come play here. Joel Embiid was drafted by the Sixers. So was Allen Iverson. So was Ben Simmons (maybe not great, but an All-Star). Even sub-immortals like Andre Iguodala only played here because the league’s draft compelled them to.
Meanwhile, teams like the Los Angeles Lakers constantly have three bites at the apple. They can draft a great player, as they did with Magic Johnson and James Worthy. They can bring great players in via free agency, as they did with LeBron James and Shaquille O’Neal. Or they can have some unsteady combination of “player doesn’t want to go to Charlotte, somehow ends up in Los Angeles” bring them a player like Kobe Bryant. Point is, Los Angeles is such a destination, players want to go there whether the team is going to win a title or not. See also Kawhi Leonard, Paul George, and on and on.
And it’s not like this is just an NBA thing. The Dodgers’ lineup is packed with these emigrants — Freddie Freeman, Trevor Bauer, Mookie Betts, Trea Turner. The Rams just won a Super Bowl with Detroit Lions refugee Matthew Stafford. We don’t really watch a lot of hockey on the Sixers betting beat, but we remember when the Kings won a Stanley Cup with Mike Richards and Jeff Carter, so there’s that.
Why do we live here again?
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Sixers vs. Lakers Odds
Here’s the line for the Sixers and Lakers at FanDuel Sportsbook:
- Point Spread: Sixers -7 (-110), Lakers +7 (-112)
- Moneyline: Sixers -295, Lakers +240
- Total: 230
Bets We Like With a Sixers Win
Sixers to Win and Over 230 Total Points (+156, FanDuel Sportsbook)

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We’re pretty excited about this one, not going to lie. The Lakers are an abysmal defensive team. They’re giving up 114.1 points per game, 26th in the league. They are, however, 12th in the league in points scored at 111.5 per game. The last three Lakers games have all gone over 230; it’s apparent that the Lakers have decided that they’re just going to score their way into the playoff play-in and take their chances.
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Bets We Like Independent of Outcome
LeBron James Double Double (+130, Caesars Sportsbook)

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James had a triple double against the Cleveland Cavaliers two nights ago and a double double against the Washington Wizards four nights ago. The points are a virtual lock, so essentially you’re getting +130 on James getting either 10 rebounds or 10 assists. We like it.
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Matisse Thybulle Over 5.5 Points (-125, DraftKings Sportsbook)

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Thybulle’s high-scoring games — and by high-scoring, we mean when he scores six or more points — generally come in two types of games. The first is a game against a bad defensive team. The second is a game against a team that doesn’t take good care of the basketball. The Lakers are both. We’ve already touched on their defensive inefficiency. They also turn it over 14.7 times per game, 28th in the league. This is a recipe for some Thybulle thievery and at least one breakaway dunk.
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Joel Embiid Over 31.5 Points (-125, FOX Bet)
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Due to the Anthony Davis-sized hole in the Lakers’ lineup, this prop is -125 everywhere. There is no point in shopping for better odds and there is no good reason not to take it.
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Sixers vs. Lakers Prediction

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The Lakers are 4-6 in their last ten games. Each of those six losses has been by at least seven points, and three of their last four losses were by double digits. We don’t like laying points with the Sixers on the road against good teams. Fortunately, the Lakers low-key suck.
Pick: Sixers -7.5 (-110, Barstool Sportsbook)
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